Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. Left untreated and undetected, it can lead to a condition called elephantiasis. Elephantiasis elefantyasis is the result of a tropical worm infection called filariasis filaryasis. Lymphatic filariasis article about lymphatic filariasis. Lymphatic filariasis is one of the neglected diseases. The complications of lymphatic filariasis arise from severe cases that lead to elephantiasis and may result in loss of limb function in addition to physical complications, lymphatic filariasis may have emotional and societal consequences as well. In areas endemic for podoconiosis, prevalence can be 5% or higher. The most severe clinical manifestations of lf are lymphedema and elephantiasis. Lymphatic filariasis is a parasitic disease caused by microscopic, threadlike worms.
Debrah ay, mand s, specht s, marfodebrekyei y, batsa l, pfarr k, et al. If you continue browsing the site, you agree to the use of cookies on this website. The most spectacular symptom of lymphatic filariasis is elephantiasisedema with thickening of the skin and underlying tissues which was the first disease discovered to be transmitted by mosquito bites. Nonetheless, to the greeksincluding hippocrates ca 460370 bc, galen 129200 ad, and paulus aegineta 625690 adthe term elephantiasis was associated with ambiguity, implying both filariasis and leprosy 3. This is a condition where the limbs swell to the point that they resemble an elephants foreleg in size, texture and colour. Lymphatic filariasis lf is caused by the filarial nematodes wuchereria bancrofti, brugia malayi and brugia timori, which are transmitted between definitive human hosts by multiple mosquito vectors and have varying geographical distributions. A free powerpoint ppt presentation displayed as a flash slide show on id. Lymphatic filariasis, which includes the advanced form, elephantiasis often incorrectly referred to as elephantitis, causes extensive disability in several tropical and subtropical regions of the world. The threadlike worm that can cause lymphatic filariasis is a blooddwelling filarial nematode, also called a roundworm, from the aschelminth phyla reference 2. Education and information about lymphatic filariasis for health professionals including guidance for the care of patients with lymphedema, elephantiasis, hydrocele. Lymphatic filariasis elimination can viably contribute to the achievement of the millennium development goals.
According to the global alliance to eliminate lymphatic filariasis, lymphatic filariasis is a parasitic disease caused by threadlike worms living in the human lymphatic system reference 1. Apr 09, 2016 lymphatic filariasis is a parasitic disease caused by microscopic, threadlike worms that only live in the human lymph system, which maintains the bodys fluid balance and fights infections. Feb 08, 2015 the most spectacular symptom of lymphatic filariasis is elephantiasisedema with thickening of the skin and underlying tissues which was the first disease discovered to be transmitted by mosquito bites. Sep 29, 2017 elephantiasis is also known as lymphatic filariasis.
Elephantiasis results when the parasites lodge in the lymphatic system. Lymphatic filariasis united states pdf ppt case reports. Lymphatic filariasis also called elephantiasis is a vector borne disease, spread by the bite of mosquitoes and black flies. Nov 01, 2018 lymphatic filariasis is a disease caused by parasitic roundworms of 3 different types. Lymphatic filariasis infects 120 million people in 73 countries worldwide and continues to be a worsening problem, especially in africa and the indian subcontinent. Lymphatic filariasis has been known to occur in the nile region, and ancient artifacts suggest that the disease may have been present as early as 2000bc. These worms occupy the lymphatic system, including the lymph nodes. When lymphatic filariasis develops into chronic conditions, it leads to lymphoedema tissue swelling or elephantiasis skintissue thickening of limbs and hydrocele scrotal swelling. Find powerpoint presentations and slides using the power of, find free presentations research about filariasis ppt about 22 results 0. Clinical and pathological aspects of filarial lymphedema and its. Filariasis any one of several helminthic diseases of man and animals caused by the. While the infection is usually acquired in childhood, its visible manifestations occur later in life, causing temporary or permanent disability.
Lymphatic filariasis, commonly known as elephantiasis, is a neglected tropical disease. If so, share your ppt presentation slides online with. When infected mosquitoes transmit the parasitic worm wuchereria bancrofti to people, the worm blocks the lymphatic system. In chronic case of infection, these worms may give rise to. Recently we have been receiving many inquiries related to a national eradication programme of lymphatic filariasis lf, a chronic condition that can result in elephantiasis. Although the immune responses to filarial parasites have been well studied with respect to natural history, diagnosis, and treatment, there is a relative paucity of information in terms of the mechanisms underlying development of pathology. Dec has been used worldwide for more than 50 years. Lymphatic filariasis, or elephantiasis, is a serious threat to approximately 406 million people in the african region. Elephantiasis affects mainly the lower extremities, while the ears.
Lymphatic filariasis dan imler morning report epidemiology w. Ppt lymphatic filariasis powerpoint presentation free. Elephantiasis is also known as lymphatic filariasis. The skin may become thicker as well, and the condition may become painful. Its caused by parasitic worms, and can spread from person to person through mosquitoes. Lf is common in tropical and subtropical regions an estimated 120 million people in 81 countries are infected, a third of whom have overt clinical. Elephantiasis, also known as lymphatic filariasis, is a very rare condition thats spread by mosquitoes the common name is often used because if you have it, your arms and legs can swell and. Lymphatic filariasis discovery stanford university.
The adobe flash plugin is needed to view this content. Nov 19, 2011 this is a very old case of filariasis, now converted to elephantiasis which means elephant like leg due to thickening of skin. Elephantiasis pictures, symptoms, causes, diagnosis. Like onchocerciasis, lymphatic filariasis is caused by filarial worms and is vectorborne. Wuchereria bancrofti, brugia malayi, or brugia timori. People with lymphedema and elephantiasis are unlikely to benefit from dec treatment because most people with lymphedema. Lymphatic filariasis, commonly known as elephantiasis, is an infection in humans caused by the transmission of certain parasites known as filariae filarial. This blockage causes fluids to collect in the tissues, which can lead to great swelling, called lymphedema, the legs of patient seems as leg of elephant in appearance so called elephantiasis in stead of lymphatic filariasis.
Lymphatic filariasis is spread from person to person by mosquitoes. Ppt lymphatic filariasis elephantiasis powerpoint presentation free to download id. Addiss d, filariasis global alliance to eliminate lymphatic 2010 the 6th meeting of the global alliance to eliminate lymphatic filariasis. Lymphatic filariasis risk risk of lymphatic filariasis is present in tanzania. It was not until 807870 ad that ali ibn sahl rabban altabbari first described elephantiasis as daa. Cp ramachandran fasc akademi sains malaysia, researcher interview at bfm 89. Oct 02, 2010 lymphatic filariasis and onchocerciasis. Elephantiasis is a late manifestation of lymphatic filariasis, which apart from limbs may involve genitalia or breasts. Lymphatic filariasis, considered globally as a neglected tropical disease ntd, is a parasitic disease caused by microscopic, threadlike worms. The worms invade the lymphatic system of our body causing injury to lymph nodes. Mar 16, 2018 diethylcarbamazine dec is the drug of choice in the united states. The worms multiply in the body and create blockages within the lymphatic system. The blockage causes swelling in the legs or other parts of the body, making these body parts appear large and puffy, or elephantlike. This disorder is parasitic infection since it is caused by worms and these worms are transmitted into the body by mosquitoes and black flies.
These are two different diseases but they both cause enlargement of lower extremities that would appear like an elephants limb and thus accountable for the term. Lymphatic filariasis, filariasis vector, filariasis. Lymphatic filariasis genetic and rare diseases information. Lymphatic filariasis can progress to elephantiasis, a swelling and thickening of body tissues from accumulation of fluid. Lymphatic filariasis is transmitted via mosquitoes and is caused by either of the following parasitic worms. Doxycycline reduces plasma vegfc svegfr3 and improves pathology in lymphatic filariasis. The infection is usually acquired in childhood but the painful and profoundly disfiguring disease often occurs later in life. The parasite larva develops into an adult worm inside the body.
Knowing that the person lives in or has spent time in a country where filariasis poses a risk can help a doctor diagnose the disease. Learn to prevent lymphatic filariasis by avoiding mosquito bites that spread the disease, and recognize when infection is present. There are 3 known species of the filarial nematode that can cause lymphatic filariasis. This is a very old case of filariasis, now converted to elephantiasis which means elephant like leg due to thickening of skin. Morbidity management and disability prevention in lymphatic filariasis 1 1. A longstanding infection with lymphatic filariasis results in a condition called elephantiasis, in which changes in the affected limbs result in hardening that resembles elephant skin.
In the human body, the disease parasite is acquired during childhood causing a gradual damage in lymphatic system. Disability and quality of life in patients with lymphatic. Name two severe deformities seen in clinical manifestations of lymphatic filariasis and the areas of the body in which they are found. Some people, however, develop a syndrome called elephantiasis, which is.
It is caused by infection with parasites classified as. These worms live in, and cause damage to, the lymphatic system that normally returns fluids in our extremities to the circulatory system. Filariasis is caused by wucherirai banchorafti, spread by mosquito bites. The disease is caused by a parasite transmitted by mosquito bites.
It is most commonly caused by wuchereria bancrofti, and may also be caused by brugia malayi and brugia timori. Some studies have shown adult worm killing with treatment with doxycycline 200mgday for 46 weeks. A statue of pharaoh mentuhotep ii depicts swollen limbs, a characteristic of elephantiasis, which is a symptom of heavy lymphatic filariasis infection. Insights into the pathogenesis of disease in human. Lymphatic filariasis, also known as elephantiasis, is a parasitic infection caused by the wuchereria bancrofti, b rugia malayi, and brugia timori nematode worms transmitted to humans through the bite of infected aedes, culex, anopheles, and mansonia mosquitoes. In endemic communities, approximately 10 percent of women can be affected with swollen limbs and 50 percent of men can have from mutilating genital disease.
It is highly disabling and stated to be the second leading cause of long term disability and socioeconomic consequences in. Lymphatic filariasis elephantiasis is the property of its rightful owner. Lymphatic filariasis introduction stanford university. This is an advanced stage of the illness whereby body parts such as the limbs and the genitals can become irreversibly swollen due to disturbed drainage of the lymph vessels in the skin. Treatment for lymphatic filariasis and elephantiasis. Is a nematode that causes lymphatic filariasis, also known as elephantiasis, ppt. Global alliance to eliminate lymphatic filariasis lymphatic filariasis or elephantiasis a major cause of permanent. Without community health education to help inform people about lymphatic filariasis, the affected individual is more likely to be highly stigmatized in his or. This results in fluid collection in various tissues of the body. Elephantiasis or lymphatic filariasis with treatment youtube. Lymphatic filariasis is a disease that is on the world health organizations who top ten list of diseases to eliminate by 2020.
View and download powerpoint presentations on lymphatic filariasis in children ppt. Lymphatic filariasis, commonly known as elephantiasis, is a painful and profoundly disfiguring disease. Insights into the pathogenesis of disease in human lymphatic. The lymph system maintains the bodys fluid balance and fights infections. Elephantiasis is a common term for either lymphatic filariasis or podoconiosis. Infection occurs when filarial parasites are transmitted. Hydrocele scrotum lymphedema elephantiasis extremities i. It is a parasitic disease caused by the filial worms parasitic worms. Filarial excretorysecretory products induce human monocytes to. People with the disease can suffer from lymphedema and elephantiasis and in men, swelling of the scrotum, called hydrocele. Wuchereria bancrofti, brugia malayi and brugia timori. In settings where onchoceriasis is present, ivermectin is the drug of choice to treat lf.
Ppt lymphatic filariasis powerpoint presentation free to. The adult worms only live in the human lymph system. Lymphatic filariasis, filariasis vector, filariasis symptoms. Sep 15, 2014 recently we have been receiving many inquiries related to a national eradication programme of lymphatic filariasis lf, a chronic condition that can result in elephantiasis. Lymphatic filariasis is caused by thin worms transmitted to humans by the bites of mosquitoes in tropical and subtropical regions. Mar 17, 2020 people suffering from the disease may have lymphedema swelling from fluid buildup and elephantiasis engorgement and thickened skin, often of the leg.
According to the world health organization, lymphatic filariasis, a mosquitoborne parasitic disease, is the second leading cause of disability worldwide. Lymphatic filariasis is caused by a threadlike parasitic worm that is transmitted by mosquitoes. People suffering from the disease may have lymphedema swelling from fluid buildup and elephantiasis engorgement and thickened skin, often of the leg. Skip directly to site content skip directly to page options skip directly to az link. The drug kills the microfilariae and some of the adult worms. Some people, however, develop a syndrome called elephantiasis, which is marked by severe swelling in the arms, legs, breasts, or genitals. Lymphatic filariasis who regional office for africa. This thickening of the skin and swelling of underlying tissues is caused by parasites lodged in the lymphatic system, a network of channels, nodes and. The global programme to eliminate lymphatic filariasis, launched following world health assembly resolution 50. Elephantiasis causes swelling of the scrotum, legs. Across 81 countries, approximately 120 million people are infected with the disease, and of those infected, an estimated 40% reside in india alone. The lymph system maintains the bodys fluid balance and. Lymphatic filariasis is a parasitic disease caused by microscopic, threadlike worms that only live in the human lymph system, which maintains the bodys fluid balance and fights infections. The name comes from the severe swelling of the limbs that occurs during the chronic state of the disease.